Kaohsiung Journal of Medical Sciences
Volume 23, Issue 9 , Pages 470-474, September 2007

Biloma Following Transcatheter Arterial Chemoembolization with Microspheres: A Case Report

  • Chao-Kuan Huang

      Affiliations

    • Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • Graduate Institute of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
  • ,
  • Shinn-Cherng Chen

      Affiliations

    • Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
  • ,
  • Paul Ming-Chen Shih

      Affiliations

    • Department of Medical Imaging, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
  • ,
  • Wan-Long Chuang

      Affiliations

    • Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • Graduate Institute of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • Corresponding Author InformationAddress correspondence and reprint requests to: Dr Wan-Long Chuang, Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, 100 Shih-Chuan 1st Road, Kaohsiung 807, Taiwan

Received 29 January 2007; accepted 13 March 2007.

Article Outline

We report a case of inrrahepatic biloma following transcatheter arterial chemoembolization (TACE) with microspheres in a 44-year-old male patient. He was diagnosed with hepatocellular carcinoma with satellite nodules and inrrahepatic duct invasion in August 2004. TACE was performed with a mixture of lipiodol, epirubicin hydrochloride, and mitomycin followed by microspheres as devas-cularizing material. Local external irradiation was performed on the area of intrahepatic duct invasion after the first TACE. Owing to local rumor progression and growth of new rumor nodules, a series of TACEs were performed. However, fever and diarrhea developed 2 weeks after the third TACE. Biloma with infection was diagnosed and was then treated successfully with percutaneous drainage and antibiotics. Embolization using microspheres at the proximal right hepatic artery was considered to have been the jeopardizing etiologic factor of biloma formation.

Key Words:  biloma , hepatocellular carcinoma , microspheres , transcatheter arterial , chemoembolization

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PII: S1607-551X(08)70055-X

doi:10.1016/S1607-551X(08)70055-X

Kaohsiung Journal of Medical Sciences
Volume 23, Issue 9 , Pages 470-474, September 2007