Kaohsiung Journal of Medical Sciences
Volume 23, Issue 9 , Pages 475-479, September 2007

Renal Cell Carcinoma Presenting with Skull Metastasis: A Case Report and Literature Review

  • Hsin-Chih Yeh

      Affiliations

    • Department of Urology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • ,
  • Sheau-Fang Yang

      Affiliations

    • Department of Pathology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • ,
  • Hung-Lung Ke

      Affiliations

    • Department of Urology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • ,
  • Kung-Shing Lee

      Affiliations

    • Department of Neurosurgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • ,
  • Chun-Hsiung Huang

      Affiliations

    • Department of Urology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • Department of Urology, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • ,
  • Wen-Jeng Wu

      Affiliations

    • Department of Urology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • Department of Urology, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • Corresponding Author InformationAddress correspondence and reprint requests to: Dr Wen-Jeng Wu, Department of Urology, Kaohsiung Medical University Hospital, 100 Shih-Chuan 1st Road, Kaohsiung 807, Taiwan

Received 24 November 2006; accepted 25 April 2007.

The occurrence of metastasis to the head and neck region in renal cell carcinoma is extremely rare. An 80-year-old man presented with a soft nodule in the left parietal calvarium and was admitted to our hospital. Biopsy of the nodule showed nests of clear tumor cells, suggesting metastatic renal cell carcinoma. Computed tomography of the abdomen revealed a well-defined hypervas-cular tumor, measuring around 7×7×8 cm, exophytic from the lower pole of the right kidney. Since there were no other systemic metastases, right nephrectomy and complete resection of the skull lesion were performed. No adjunctive therapy was given postoperatively After 22 months of follow-up, the patient was well and without evidence of disease.

Key Words:  renal cell carcinoma , skull metastasis

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PII: S1607-551X(08)70056-1

doi:10.1016/S1607-551X(08)70056-1

Kaohsiung Journal of Medical Sciences
Volume 23, Issue 9 , Pages 475-479, September 2007

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