Kaohsiung Journal of Medical Sciences
Volume 24, Issue 5 , Pages 227-232 , May 2008

Expression of Androgen, Estrogen and Progesterone Receptors in Mucinous Carcinoma of the Breast

  • Li-Chen Cho

      Affiliations

    • Department of Nursing, Tzu Chi College of Technology, Hualien, Taiwan
    • ,
  • Yung-Hsiang Hsu

      Affiliations

    • Department of Pathology, Buddhist Tzu Chi General Hospital and University, Hualien, Taiwan
    • Corresponding Author InformationAddress correspondence and reprint requests to: Dr Yung-Hsiang Hsu, Department of Pathology, Tzu Chi General Hospital and University, 707, Section 3, Chung-Yang Road, Hualien 94007, Taiwan

Received 22 November 2007 ,Accepted 4 January 2008.

References 

  1. Moinfar F , Okcu M , Tsybrovskyy O , et al.   Androgen receptors frequently are expressed in breast carcinoma: potential relevance to new therapeutic strategies . Cancer . 2003;98:703–711
  2. Pichon MF , Broet P , Magdelenat H , et al.   Prognostic value of steroid receptors after long term follow-up of 2257 operable breast cancer . Br J Cancer . 1996;73:1545–1551
  3. Wenger CR , Beardslee S , Owens MA , et al.   DNA-ploidy, S-phase, and steroid receptors in more than 127,000 breast cancer patients . Breast Cancer Res Treat . 1993;28:9–26
  4. Foekens JA , Portensen H , Van Pautten WLJ . Prognostic value of estrogen and progesterone receptors measured by enzyme immunoassay in human breast tumor cytosols . Cancer Res . 1989;49:5823–5828
  5. Lillie E , Bernstein L , Ursin G . The role of androgens and polymorphisms in the androgen receptor in the epidemiology of breast cancer . Breast Cancer Res Treat . 2003;5:164–173
  6. Ellis LM , Wittliff L , Bryant MS . Correlation of estrogen, progesterone and androgen receptors in breast cancer . Am J Surg . 1989;157:577–581
  7. Soreide JA , Lea OA , Varhaug JE , et al.   Androgen receptors in operable breast cancer: relation to other steroid hormone receptors, correlations to prognostic factors and predictive value for effect of adjuvant tamoxifen treatment . Eur J Surg Oncol . 1992;18:112–118
  8. Kuenen-Boumeester V , Van der Kwast TH , van Putten WL , et al.   Immunohistochemical determination of androgen receptors in relation to oestrogen and progesterone receptors in female breast cancer . Int J Cancer . 1992;52:581–584
  9. Scopsi L , Andreola S , Pilotti S , et al.   Mucinous carcinoma of the breast . Am J Surg Pathol . 1994;18:702–711
  10. Avisar E , Khan MA , Axelrod D , et al.   Pure mucinous carcinoma of the breast: a clinicopathologic correlation study . Ann Surg Oncol . 1998;5:447–451
  11. Brown RW , Chirala R . Utility of microwave-citrate antigen retrieval in diagnostic immunohistochemistry . Mod Pathol . 1995;8:515–520
  12. Barnes DM , Hanby AM . Oestrogen and progesterone receptors in breast cancer: past, present and future . Histopathology . 2001;38:271–274
  13. Lippman M , Bolan G , Huff K . The effects of andro-gens and antiandrogens on hormone-responsive human breast cancer in long-term tissue culture . Cancer Res . 1976;36:4610–4618
  14. Brinkmann AO , Blok LJ , de Ruiter PE , et al.   Mechanism of androgen receptor activation and function . J Steroid Biochem Mol Biol . 1999;69:307–313
  15. Gatalica Z . Immunohistochemical analysis of apocrine breast lesions. Consistent over-expression of andro-gen receptor accompanied by the loss of estrogen and progesterone receptors in apocrine metaplasia and apocrine carcinoma in situ . Pathol Res Pract . 1997;193:753–758
  16. Riva C , Daihese E , Caprara G , et al.   Immunohistochemical study of androgen receptors in breast carcinoma. Evidence of their frequent expression in lobular carcinoma . Virchows Arch . 2005;447:695–700
  17. Honma N , Sakamoto G , Akiyama F , et al.   Breast carcinoma in women over the age of 85: distinct histological pattern and androgen, oestrogen, and progesterone receptor status . Histopathology . 2003;42:120–127
  18. Shousha S , Coady AT , Stamp T , et al.   Estrogen receptors in mucinous carcinoma of the breast: an immuno-histochemical study using paraffin wax sections . J Clin Pathol . 1989;42:902–905
  19. Chu JS , Chang KJ . Mucin expression in mucinous carcinoma and other invasive carcinomas of the breast . Cancer Lett . 1999;142:121–127
  20. Wako K , Kawasaki T , Yamana K , et al.   Expression of androgen receptor through androgen-converting enzymes is associated with biological aggressiveness in prostate cancer . J Clin Pathol . 2007; Aug 24; [Epub ahead of print]
  21. Jackson KM , Frazier MC , Harris WB . Suppression of androgen receptor expression by dibenzoylmethane as a therapeutic objective in advanced prostate cancer . Anticancer Res . 2007;27:1483–1488

PII: S1607-551X(08)70146-3

doi: 10.1016/S1607-551X(08)70146-3

Kaohsiung Journal of Medical Sciences
Volume 24, Issue 5 , Pages 227-232 , May 2008

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