Kaohsiung Journal of Medical Sciences
Volume 24, Issue 5 , Pages 262-269, May 2008

Low-Grade Astrocytoma Associated with Abscess Formation: Case Report and Literature Review

  • Tai-Hsin Tsai

      Affiliations

    • Department of Neurosurgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • ,
  • Yan-Fen Hwang

      Affiliations

    • Department of Neurosurgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • ,
  • Shiuh-Lin Hwang

      Affiliations

    • Department of Neurosurgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • Department of Surgery, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • ,
  • Chen-Hsiang Hung

      Affiliations

    • Department of Neurosurgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • ,
  • Cheng-Wei Chu

      Affiliations

    • Department of Neurosurgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • ,
  • Boon-Kee Lua

      Affiliations

    • Department of Neurosurgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • ,
  • Chih-Lung Lin

      Affiliations

    • Department of Neurosurgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • Department of Surgery, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • ,
  • Kung-Shing Lee

      Affiliations

    • Department of Neurosurgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • Department of Surgery, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • ,
  • Joon-Khim Loh

      Affiliations

    • Department of Neurosurgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • Department of Surgery, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • ,
  • Aij-Lie Kwan

      Affiliations

    • Department of Neurosurgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • Department of Surgery, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • ,
  • Chih-Jen Wang

      Affiliations

    • Department of Neurosurgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • Department of Surgery, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • ,
  • Tzuu-Yuan Huang

      Affiliations

    • Department of Neurosurgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • Department of Surgery, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • ,
  • Shen-Long Howng

      Affiliations

    • Department of Neurosurgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • Department of Surgery, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • ,
  • Ann-Shung Lieu

      Affiliations

    • Department of Neurosurgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • Department of Surgery, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • Corresponding Author InformationAddress correspondence and reprint requests to: Dr Ann-Shung Lieu, Department of Neurosurgery, Kaohsiung Medical University Hospital, 100 Tzyou 1st Road, Kaohsiung 807, Taiwan

Received 4 September 2007; accepted 5 October 2007.

Article Outline

A rare case of low-grade astrocytoma associated with abscess formation occurred in a 52-year-old man presenting with Broca's aphasia. He underwent craniotomy and tumor removal under the impression of brain tumor with necrotic cystic change. Abscess accumulation within the intra-axial tumor was found intraoperatively. Literature related to brain abscess with brain tumor is reviewed, with an emphasis on abscesses with astrocytoma. We discuss the common brain tumors that are associated with abscess, pathogens that coexist with brain tumor, and the pathogeneses of coexisting brain abscess and tumor. It is very important to know how to differentiate between and diagnose a brain abscess and tumor, or brain abscess with tumor, preoperatively from clinical presentation and through the use of computed tomography, conventional magnetic resonance imaging, diffusion-weighted imaging or magnetic resonance spectroscopy.

Key Words:  astrocytoma , brain abscess , magnetic resonance spectroscopy

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References 

  1. Walker DG , Kaye AH . Low grade astrocytomas: controversies in management . J Clin Neurosci . 2000;7:475–480
  2. Walker DG , Kaye AH . Low grade glial neoplasms . J Clin Neurosci . 2003;10:1–13
  3. Loiseau H , Dartigues JF , Cohadon F . Low-grade astro-cytomas: prognostic factors and elements of management . Surg Neurol . 1995;44:224–227
  4. Karampekios S , Hesselink J . Cerebral infections . Eur Radiol . 2005;15:485–493
  5. Yoshikawa TT , Goodman SJ . Brain abscess . West J Med . 1974;121:207–219
  6. Mohindra S , Gupta R . Posterior-fossa intra-tumoural abscess: a report of three patients and literature review . Br J Neurosurg . 2004;18:556–560
  7. Zhang X , Li Q , Hu P , et al.   Two case reports of pituitary adenoma associated with Toxoplasma gondii infection . J Clin Pathol . 2002;55:965–966
  8. Jadhav RN , Dahiwadkar HV , Palande DA . Abscess formation in invasive pituitary adenoma: case report . Neurosurgery . 1998;43:616–619
  9. Ichikawai M , Shimizu Y , Manabu Sato M , et al.   Abscess within a glioblastoma multiforme . Neurol Med Chir (Tokyo) . 1992;32:829–833
  10. Hatiboglu MA , Iplikcioglu AC , Ozcan D . Abscess formation within invasive pituitary adenoma . J Clin Neurosci . 2006;13:774–777
  11. Shanley DJ , Holmes SM . Salmonella typhi abscess in a craniopharyngioma: CT and MRI . AJNR Am J Neuroradiol . 1994;36:35–36
  12. Obrador S , Blazquez MG . Pituitary abscess in a cranio-pharyngioma. Case report . J Neurosurg . 1972;36:785–789
  13. Bansal S , Vasishta RK , Pathak A , et al.   Cerebral abscess with astrocytoma . Neurol India . 2001;49:91–93
  14. Nassar SI , Haddad FS , Hanbali FS . Abscess superimposed on brain tumor: two case reports and review of the literature . Surg Neurol . 1997;47:484–488
  15. Shimomura T , Hori S , Kasai N , et al.   Meningioma associated with intratumoral abscess formation . Neurol Med Chir (Tokyo) . 1994;34:440–443
  16. Yeates KE , Halliday W , Miyasaki J , et al.   A case of circling seizures and an intratumoral abscess . Clin Neurol Neurosurg . 2003;105:128–131
  17. Eisenberg MB , Lopez R , Stanek AE . Abscess formation within a parasagittal meningioma. Case report . J Neurosurg . 1998;88:895–897
  18. Young JP , Young PH . Meningioma associated with abscess formation-a case report . Surg Neurol . 2005;63:584–585
  19. Onopchenko EV , Grigorian IA . Meningioma with a peritumoral abscess . Zh Vopr Neirokhir Im N N Burdenko . 1999;1:28–30
  20. Lind CR , Muthiah K , Bok AP . Peritumoral Citrobacter koseri abscess associated with parasagittal meningioma . Neurosurgery . 2005;57:E814
  21. Kovacic S , Bunc G , Krajnc I . Abscess formation within cerebellar metastatic carcinoma-report of two cases and review of the literature . Wien Klin Wochenschr . 2004;116:60–63
  22. Ng WP , Lozano A . Abscess within a brain metastasis . Can J Neurol Sci . 1996;23:300–302
  23. Lai PH , Ho JT , Chen WL , et al.   Brain abscess and necrotic brain tumor: discrimination with proton MR spectroscopy and diffusion-weighted imaging . AJNR Am J Neuroradiol . 2002;23:1369–1377
  24. Leuthardt EC , Wippold FJ , Oswood MC , et al.   Diffusion-weighted MR imaging in the preoperative assessment of brain abscesses . Surg Neurol . 2002;58:395–402

PII: S1607-551X(08)70151-7

doi:10.1016/S1607-551X(08)70151-7

Kaohsiung Journal of Medical Sciences
Volume 24, Issue 5 , Pages 262-269, May 2008

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