Kaohsiung Journal of Medical Sciences
Volume 24, Issue 10 , Pages 542-547, October 2008

Dual-Phase 99MTc-MIBI Parathyroid Imaging Reveals Synchronous Parathyroid Adenoma and Papillary Thyroid Carcinoma: A Case Report

  • Ming-Che Chang

      Affiliations

    • Department of Nuclear Medicine, Changhua Christian Hospital, Changhua, Taichung, Taiwan
    • ,
  • Shih-Chuan Tsai

      Affiliations

    • Department of Nuclear Medicine, Taichung Veterans General Hospital, Taichung, Taiwan
    • ,
  • Wan-Yu Lin

      Affiliations

    • Department of Nuclear Medicine, Taichung Veterans General Hospital, Taichung, Taiwan
    • Corresponding Author InformationAddress correspondence and reprint requests to: Dr Wan-Yu Lin, Department of Nuclear Medicine, Taichung Veterans General Hospital, 160, Taichung Harbor Road, Section 3, Taichung 407, Taiwan

Received 11 January 2008; accepted 24 March 2008.

Article Outline

The possibility of a coincidental appearance of hyperparathyroidism and thyroid cancer is not often considered because of its low incidence. Here, we present a case of a 49-year-old woman with a parathyroid adenoma coexisting with two sites of papillary thyroid carcinoma. Dual-phase 99mTc-methoxyisobutylisonitrile (MIBI) parathyroid imaging before the operation correctly visualized the site of the parathyroid adenoma. In addition, two papillary thyroid carcinomas showed faint uptake of 99mTc-MIBI on delayed image. Total thyroidectomy and parathyroidectomy of a solitary parathyroid adenoma were performed. The patient subsequently underwent radioiodine-131 ablation and was treated with T4 suppression. This case illustrates the need for clinical awareness of concomitant hyperparathyroidism and thyroid cancer. Dual-phase 99mTc-MIBI parathyroid imaging may be useful for detecting indolent thyroid cancer before it becomes a distinct disease.

Key Words:  dual-phase MIBI parathyroid imaging , hyperparathyroidism , parathyroid adenoma , thyroid carcinoma

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PII: S1607-551X(09)70014-2

doi:10.1016/S1607-551X(09)70014-2

Kaohsiung Journal of Medical Sciences
Volume 24, Issue 10 , Pages 542-547, October 2008

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