Kaohsiung Journal of Medical Sciences
Volume 25, Issue 1 , Pages 25-28, January 2009

Diabetic Muscle Infarction in Association with Terlipressin Therapy: A Case Report

  • Yu-Hung Chang

      Affiliations

    • Graduate Institute of Medicine, Kaohsiung, Taiwan
    • Division of Endocrinology and Metabolism, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • ,
  • Feng-Chieh Yen

      Affiliations

    • Division of Endocrinology and Metabolism, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • ,
  • Ming-Chia Hsieh

      Affiliations

    • Graduate Institute of Medical Genetics, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • Division of Endocrinology and Metabolism, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • ,
  • Kun-Der Lin

      Affiliations

    • Graduate Institute of Medicine, Kaohsiung, Taiwan
    • Division of Endocrinology and Metabolism, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • ,
  • Shyi-Jang Shin

      Affiliations

    • Graduate Institute of Medical Genetics, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • Division of Endocrinology and Metabolism, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • ,
  • Shih-Chieh Hsin

      Affiliations

    • Division of Endocrinology and Metabolism, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • Corresponding Author InformationAddress correspondence and reprint requests to: Dr Shih-Chieh Hsin, Department of Endocrinology and Metabolism, Kaohsiung Medical University Hospital, 100 Shin-Chuan 1st Road, Kaohsiung 807, Taiwan

Received 20 April 2008; accepted 24 July 2008.

Article Outline

Diabetic muscle infarction (DMI) is a rare complication that often exists in long-standing diabetic patients. Clinically, it presents with pain, swelling and sometimes a palpable mass, and is often misdiagnosed as soft tissue infection. The athogenesis of DMI is uncertain. We present the case of a type 2 diabetic patient with liver cirrhosis who was diagnosed with muscle infarction after being treated with terlipressin for gastrointestinal bleeding. This 45-year-old male complained of increasing pain in his right posterior thigh after treatment with terlipressin for 2 days. He was initially diagnosed with soft tissue infection, but he responded poorly to antibiotic treatment. Magnetic resonance imaging suggested acute muscle infarction. We performed a muscle biopsy and the pathologist reported that the muscle was necrotic. After 5 days of bed rest, the patient was able to walk and was discharged uneventfully.

Key Words:  diabetic muscle infarction , terlipressin

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PII: S1607-551X(09)70036-1

doi:10.1016/S1607-551X(09)70036-1

Kaohsiung Journal of Medical Sciences
Volume 25, Issue 1 , Pages 25-28, January 2009

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