Kaohsiung Journal of Medical Sciences
Volume 26, Issue 6 , Pages 333-336, June 2010

Alexithymia Associated With Bilateral Globus Pallidus Lesions After Carbon Monoxide Poisoning

  • Mei-Feng Huang

      Affiliations

    • Department of Psychiatry, Kai-Suan Psychiatric Hospital; Kaohsiung, Taiwan
  • ,
  • Yi-Chun Yeh

      Affiliations

    • Department of Psychiatry, Kaohsiung Medical University Hospital; Kaohsiung, Taiwan
  • ,
  • Hin-Yeung Tsang

      Affiliations

    • Department of Psychiatry, Kai-Suan Psychiatric Hospital; Kaohsiung, Taiwan
  • ,
  • Cheng-Sheng Chen

      Affiliations

    • Department of Psychiatry, Kaohsiung Medical University Hospital; Kaohsiung, Taiwan
    • Department of Psychiatry, Faculty of Medicine, Kaohsiung, Taiwan
    • Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • Corresponding Author InformationAddress correspondence and reprint requests to: Dr Cheng-Sheng Chen, Department of Psychiatry, Kaohsiung Medical University, 100 Tzyou 1st Road, Kaohsiung 807, Taiwan

Received 12 August 2009; accepted 9 October 2009.

Alexithymia refers to a person's inability to identify and describe feelings. We present a patient who developed alexithymia after carbon monoxide poisoning following a suicide attempt by burning charcoal in an enclosed space. Brain computed tomography revealed bilateral globus pallidus hypoxic lesions. Because of the time frame and the presence of brain structural lesions, the alexithymia in this patient was thought to be caused by bilateral globus pallidus hypoxic lesions resulting from carbon monoxide poisoning. The alexithymia in this patient did not respond to a variety of psychotropic drugs, including sertraline, venalfaxine, bupropion or methylphenidate. We suggest that alexithymia, which was associated with brain hypoxic lesions in this case, is resistant to treatment.

Key Words:  alexithymia , carbon monoxide poisoning , globus pallidus

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PII: S1607-551X(10)70048-6

doi:10.1016/S1607-551X(10)70048-6

Kaohsiung Journal of Medical Sciences
Volume 26, Issue 6 , Pages 333-336, June 2010